Medically reviewed by Steffini Stalos, DO Key Takeaways CD4 T helper cells help the body fight infections by signaling other cells to attack germs. Without enough CD4 T cells, the body can't fight ...

This study, led by Dr. Panpan Jiang and collaborators at Tongji Medical College, explores the critical role of the Dedicator of Cytokinesis 8 (DOCK8) gene in the differentiation of helper T cells, ...

Scientists analyzing human and mouse pancreatic lymph nodes (PLNs) and spleens have identified a distinct subset of CD4 memory helper T cells associated with type 1 diabetes (T1D). Reported by ...

In a person living with HIV, proviruses—strands of HIV DNA—are typically integrated into the T cell genome and become a permanent part of the cell's genetic makeup. This integration enables the ...

Researchers have used a new method, ReapTEC, to identify rare types of helper T cells that are associated with immune disorders. The immune system is largely made up of a type of white blood cell ...

Helper T cells like this one are arguably among the most important components of the immune system. They help activate many other cells and processes in the immune system, increasing its overall ...

During infections, the immune system needs to distinguish foreign molecules from invading bacteria and viruses from molecules that are made by cells of the body. If it can’t, the immune system can ...

Study reveals that moderate fever temperatures (39°C) improve metabolism, proliferation, and effector function of CD4 T cells while reducing regulatory T cell suppression. Study: Subset-specific ...

Researchers at Johns Hopkins Medicine have reported evidence that standard chemotherapeutic drugs may selectively suppress HIV-infected immune cell clones, an observation that could inform future ...

Fever temperatures rev up immune cell metabolism, proliferation and activity, but they also—in a particular subset of T cells—cause mitochondrial stress, DNA damage and cell death, Vanderbilt ...