Delta-like protein 1 (DLK1) is an enigmatic member of the epidermal growth factor-like family that plays a pivotal role in regulating cell proliferation, differentiation and tissue development. Acting ...

Scientists have discovered how two transcription factors form a reciprocal regulatory circuit that controls T-cell exhaustion ...

A comprehensive map of aberrant hematopoiesis in people with acute myeloid leukemia defines specific cell states and potential therapeutic targets. The team used their reference map for normal ...

CD8 + cytotoxic T lymphocytes (CTLs) serve as central effectors in cancer immunotherapy by directly eliminating tumor cells. However, current clinical therapies face significant limitations. These ...

B-cell acute lymphoblastic leukemia is the most common form of childhood cancer. In this type of cancer, which affects blood ...

A new preclinical study found that inhibiting the enzyme LSD1 can activate the skin’s immune system and suppress tumor growth ...

Prostate cancer affects one in five Australian men, making it the most common cancer in the country. Now, researchers at the ...

A new study published in Science China Life Sciences shows that inhibition of Aurora kinases can promote the differentiation of liver cancer cells. The research was conducted by scientists from Peking ...

A study published in Cell Research advances a central idea in stem cell biology by identifying a checkpoint that controls the ...

A study reveals that T cells can reside in prostate tissue for long periods, adapting to fight infections. These insights ...

As we venture further into space and increasingly use low Earth orbit for in-space manufacturing, the potential for the development of innovative technologies appears to be infinite. For these ...