Several computational methods based on microarray data are currently used to study genome-wide transcriptional regulation. Few studies, however, address the combinatorial nature of transcription, a ...

Safety analysis of lurbinectedin versus topotecan in elderly patients. This is an ASCO Meeting Abstract from the 2023 ASCO Annual Meeting I. This abstract does not include a full text component.

Polymorphic drug-metabolizing enzymes (DME) are likely to represent some of the most common inheritable risk factors associated with common 'disease' phenotypes, such as adverse drug reactions. The ...

A matrix comparison method is demonstrated for measuring the relative dispersion of different classes of individuals (e.g., species, age classes, life forms) in a sample of plants whose distributions ...

We propose a hybrid heuristic procedure based on scatter search and tabu search for the problem of clustering objects to optimize multiple criteria. Our goal is to search for good approximations of ...