For stem cells to differentiate into the appropriate cell-type, transcription factors (TFs) must be tailored to highly specific expression patterns of lineage-specific genes. Abnormalities in the ...

Researchers at the Hong Kong University of Science and Technology (HKUST) have found how stem cells’ surrounding environment controls them to differentiate into functional cells, a breakthrough ...

Northwestern Medicine scientists have identified the cellular mechanisms that cause immune cells to differentiate and ultimately lose function during viral infection, findings that could improve ...