HIV-1 protease inhibitors (PIs) have long been central to antiretroviral therapy, directly targeting the enzyme responsible for processing viral polyproteins into functional units. Their efficacy, ...

Colorectal cancer is one of the most prevalent tumors and a leading cause of cancer-related mortality. Despite advances achieved in recent years, resistance to available treatments remains one of the ...

Lymphomas belong to the group of malignant diseases of the immune system and mainly affect the organs of the lymphatic system. Anaplastic large cell lymphoma (ALCL) belongs to the subgroup of ...

Please provide your email address to receive an email when new articles are posted on . New therapies for muscular dystrophy must go beyond traditional corticosteroid administration. Treatments that ...

A research team led by Prof. Zhou Rongbin from the University of Science and Technology of China (USTC) discovered the mechanism by which lysophosphatidylserine (LysoPS) inhibits the anti-tumor ...

Scientists have identified how an enzyme involved in DNA repair (POLQ), becomes vital to the survival of certain cancers, if the cancer cells lose the ability to use a more common method of DNA repair ...

An international study led by scientists at Flinders University and at South China University of Technology has uncovered a new vulnerability in prostate cancer cells that could help improve treatment ...

Among patients with idiopathic pulmonary fibrosis, the risk for all-cause mortality was significantly lower with vs. without angiotensin-converting enzyme inhibitor use started within 5 years before ...

Inhibiting an overabundant enzyme saved a key component of a brain signaling pathway that is vital for motor control in a new mouse study, bolstering the prospects for the biotechs currently targeting ...

Enzymes are biological catalysts that speed up chemical reactions in living organisms. They are essential for life, as they play a crucial role in various biological processes, such as digestion, ...