Scientists have elucidated the molecular mechanism by which LEM-3 cuts DNA bridges during cytokinesis. If DNA bridges persist between chromosomes during cell division, chromosomes are abnormally ...
It works on double-stranded DNA, the form most people are familiar with. However, not all DNA exists in that form. In some cases—such as certain viruses, DNA replication, and gene editing—DNA appears ...
CRISPR is a powerful DNA-editing tool that has underpinned huge advancements in human health care in the last decade. It is a ...
CRISPR functions as a programmable genetic memory system derived from bacterial immune defenses against viral infections. Guide RNA allows for rapid multiplexed targeting compared to older ...
An INRS team discovers a new family of enzymes capable of inducing targeted cuts in single-stranded DNA A few years ago, the advent of technology known as CRISPR was a major breakthrough in the ...
The discovery of CRISPR-Cas9’s gene-editing prowess revolutionized genetic engineering just over a decade ago. Now it appears that genetic engineering technology may be taking its next big leap.
Functional analysis of the LEM-3 protein and the roles of its domains using the C. elegans model. (A) Evidence shows that LEM-3 accumulates at DNA bridges remaining between daughter cells during the ...
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