Researchers at the National University of Singapore have engineered a common gut bacterium to carry a chemotherapy prodrug ...

Most chemotherapy regimens rely on systemic administration of drugs leading to a wide array of toxicities. Using viral-vector-mediated gene modification of muscle tissues, we have developed a method ...

Engineers at the University of Pennsylvania have developed a new type of lipid nanoparticle (LNP) that could one day serve as ...

Engineers at the University of Pennsylvania have built a lipid nanoparticle that chemically fuses an IDO-pathway inhibitor ...

Combination of antagonists of growth hormone-releasing hormone antagonist (GHRH) with rapamycin as a potential therapy in human breast cancers. Background: A MMC lipid-based prodrug (MLP) formulated ...

Malignant mesothelioma is an aggressive cancer that arises from the mesothelial cells of serous membranes lining the pleural, peritoneal and pericardial cavities. Pleural mesothelioma is one of the ...

Suraxavir marboxil (GP681) is an orally available prodrug that is converted in vivo to the active metabolite GP1707D07, a PA-targeting antiviral against influenza. Because GP1707D07 is primarily ...

Toxicities and doses of chemotherapy drugs in hyperthermic intraperitoneal chemotherapy (HIPEC). This is an ASCO Meeting Abstract from the 2015 ASCO Annual Meeting I. This abstract does not include a ...

Cytokines are potent immunomodulators with the potential to amplify cell-based immunity against cancer development. Interleukin-21 (IL-21) generates antitumor immunity by inducing B-cell activation ...

Kensington, MD, USA and Munich/Martinsried, Germany, March 20, 2026 (GLOBE NEWSWIRE) --Prodrug of oral amyloid beta ...