DNA repair can be divided into a set of mechanisms that identify and correct damage in DNA molecules. There are two general classes of DNA repair; the direct reversal of the chemical process ...

Scientists have elucidated the first steps of transcription-coupled repair (TCR), a critical but still mysterious mechanism of DNA repair. When genetic information is being transcribed from DNA to RNA ...

Researchers are just beginning to understand the ramifications of the fundamental discoveries behind the 2015 Nobel Prizes in Chemistry awarded to three scientists for explaining how cells repair ...

Researchers at the University of Toronto and partner hospitals have discovered a DNA repair mechanism that advances understanding of how human cells stay healthy – a finding that could lead to new ...

Identification of a previously uncharacterized genetic disease highlights DNA repair as a shared mechanism in neurodegenerative disorders, and suggests potential therapeutic approaches to tackling ...

A research team led by Professor ZHAO Guoping at the Hefei Institutes of Physical Science of the Chinese Academy of Sciences, has unveiled a crucial mechanism that helps regulate DNA damage repair, ...

For the first time, researchers have witnessed the spontaneous repair of damage to DNA molecules in real time. They observed this at the level of a single DNA molecule. Insight into this type of ...

The Philadelphia (Ph) chromosome resulting from reciprocal t(9;22) translocation was the first reported chromosomal rearrangement linked to a human malignancy. 1 The Ph chromosome results in BCR-ABL1 ...

Researchers at EMBL’s European Bioinformatics Institute (EMBL-EBI), the University of Dundee and the Wellcome Sanger Institute analyzed over 2700 genomes from C. elegans worms in order to better ...