Braunschweig, U., Gueroussov, S., Plocik, A. M., Graveley, B. R. and Blencowe, B. J. Dynamic Integration of Splicing within Gene Regulatory Pathways. Cell 152, 1252 ...
A new spatial transcriptomic approach captures the regulation of splicing and polyadenylation sites during pubescent brain development at near-single-cell resolution. An international collaboration, ...
Defining the mechanistic interface between post-transcriptional RNA regulation and chromatin regulation that controls transcriptional and epigenetic programs underlying stem cell maintenance, cellular ...
PHILADELPHIA - When most genes are transcribed, the nascent RNAs they produce are not quite ready to be translated into proteins - they have to be processed first. One of those processes is called ...
RNA repair pathways rely on RNA ligases to maintain or manipulate RNA structure in response to biologically purposeful RNA cleavage events. The goal of this project is to illuminate the mechanisms and ...
Recent research on Arabidopsis thaliana flowering may sow the seed of new connections between plant and human reproduction. Gordon Simpson and Caroline Dean at the John Innes Center in Norwich, UK, ...
The spliceosome in eukaryotes removes non-coding intronic sequences and ligates exons to produce functional messenger ribonucleic acids (mRNA) that code for proteins. However, while numerous studies ...
Braunschweig, U., Gueroussov, S., Plocik, A. M., Graveley, B. R. and Blencowe, B. J. Dynamic Integration of Splicing within Gene Regulatory Pathways. Cell 152, 1252 ...
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